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The 2016 CGU Honorary Academic Exchange Activity

The 2016 CGU Honorary Academic Exchange Activity

Office of Research and Development

To promote academic exchange and pursue scholarly excellence, CGU held the 2016 Honorary Academic Exchange Activity on the 2nd of December at the International Conference Hall of the Second Medical Science Building. Approximately 400 faculty members and students participated in this event. This event was hosted by Prof. Ming-Ling Kuo, director of the Office of Research and Development. Distinguished guests including Prof. Jan-Kan Chen, vice president of CGU, and Prof. Kwang-Huei Lin, associate dean of the College of Medicine gave introductory talks as a prelude for the keynote speakers Prof. Alice Lin-Tsing Yu, academician of the Academia Sinica, Prof. Bertrand Tan, and Associate Prof. Cheng-Lung Ku.

Prof. Alice Lin-Tsing Yu started the event by giving a speech on Strategies to Target Tumor Associated Carbohydrates for Cancer Immunotherapy. She was elected as an academician for the 31st Division of Life Sciences of the Academia Sinica in 2016. She specializes in the research of tumor immunology, cancer Immunotherapy, and the clinical trial and development of dinutuximab, a chimeric Anti-GD2 monoclonal antibody. Her speech covered the recent development and importance of translational medicine, and the challenging process of developing new drugs before they go public. She particularly highlighted the future direction of biomedical research. In addition, how to bridge the gap between fundamental research and its application to the clinical medicine, as well as how to develop Taiwan into a powerhouse of biotechnology industry in the Asia-Pacific region were the main concerns of Prof. Alice Lin-Tsing Yu. It is her expectation that the concept of translational medicine can be materialized through coordinating resources and experts. She also used her own story as an example to share with students and encourage them to work hard and make a contribution to Taiwan’s biotechnology industry.

Following the speech of Prof. Alice Lin-Tsing Yu was Prof. Bertrand Tan’s talk on Finding Meaning in the Complex Language of Gene Expression. Prof. Tan, from the Department of Biomedical Sciences, was a winner of the 2015 Academia Sinica Junior Researcher Award. In his talk, Prof. Tan shared with the audience his research findings on cross-talk between multiple layers of gene regulatory mechanisms and functional decoding. Through the use of systematic tools such as RNA-Seq, RIP-Seq, ChIP-on-chip, bioinformatics analysis, coupled with cell biology or animal models, and big data analysis, Prof. Tan’s research team attempted to search for and portray the network that may modify the development and pathology of an organism. His key research findings include (1) the profiling and functional decoding of the RNA editome, and (2) the epigenetic regulatory mechanism underlying skeletal muscle differentiation.

The last keynote speaker was Associate Prof. Cheng-Lung Ku from the Graduate Institute of Clinical Medical Sciences. Through studying diseases of the immune system, he shared with the audience his findings of the human immune mechanism. One of the world’s most prestigious journals Natural Medicine published his research team’s groundbreaking work: The Production of Anti-interferon-gamma Autoantibodies through the Molecular Mimicry by Microbial Antigen. Associate Prof. Ku’s speech topic was Anti-interferon-autoantibody Disease:A Human Immunology Approach. When a patient has the Human anti-IFN-γ autoantibodies, the existing immune-activating cytokine interferon-γ will be neutralized, which may result in the impairment of the immune system, and as a consequence may cause severe mycobacterial infection. Further research indicated that this disease is highly related to Human Leukocyte Antigen (HLA). His research team provided genetic evidence to explain why this disease has been so prevalent in Taiwan and also in the entire Southeast Asia.

This event was concluded with the enthusiastic support and participation of the faculties and students. It is hoped that, through their inspiration and encouragement, the three speakers served as good examples for faculties and students to keep learning and steadily advance CGU’s research capacity.

 

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